Diethylammonium chloride

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

10 Sep - 12 Oct 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

Storage conditions: ambient temperature (10 – 30 °C)

Water solubility:

ca. 510 g/L

Conc. based on:

element (dissolved fraction)

Remarks:

measured chloride concentration

Temp.:

20 °C

pH:

ca. 1.9

Remarks on result:

other: pH determined at 23 °C

Results
Table 1 – Results of Preliminary visual estimation of water solubility

Test item amount [mg]	Added volume of distilled water [mL]	Total volume [mL]	Mixture appearance
88.4	0.1	0.1	dissolved

 

After the addition of 0.1 mL distilled water to 88.4 mg of test item, it appeared to be dissolved. According to this test, the water solubility of the test item was > 884 g/L and the preferred method for the main test was the flask method. An additional stirring test was done prior to the main test, to determine the highest amount of test item that can still be stirred sufficiently in a mixture with water.

Table 2 – Stirring test

Test item amount [g]	Added volume of distilled water [mL]	Total volume [mL]	Mixture appearance
5.51	0.5	1.0	Could not be stirred at RT
	1.0	1.5	Could be stirred at RT

 

According to this test, mixtures of ca. 1000 g/L test item in distilled water were used in the main test.

Flask Method
Water solubility was calculated from the measured unrounded concentration values and not from the rounded values below.

Table 3 – Water solubility experiments of the test item

Experiment	24 h experiment	48 h experiment	72 h experiment	Blank experiment (72 h)
Test item amount [g]	20.40	20.20	20.39	--
Distilled water amount [mL]	20
Stirring time at 30 °C [h]	24	48	72	72
pH at 23 °C	1.9			6.2
Measured chloride concentration [% m/m]	16.5	16.4	16.6	< 0.01
Test item concentration [% m/m]	51.0	50.7	51.3	< 0.1
Water solubility [g/Kg]	510.1	507.0	513.2	< 1

 

Water solubility of the test item at 20 °C was found to be 510 g/Kg.

Description of key information

510 g/L at 20 °C (OECD 105, Flask method)

Key value for chemical safety assessment

Water solubility:

510 g/L

at the temperature of:

20 °C