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EC number: 209-674-2
CAS number: 590-19-2
ecotoxicity data is only available for 6.1.3 Short term toxicity to
aquatic invertebrates. This proprietary study reports a 48hr EC50 for
Daphnia magna of 7.3mg/l.
accordance with column 2 of REACH Annex VII and VIII, the acute toxicity
tests do not need to be conducted if there are mitigating factors
indicating that aquatic toxicity is unlikely to occur. Buta-1,2-diene is
a gas at standard temperature and pressure and is expected to partition
primarily to air, therefore aquatic toxicity tests may not be relevant.
In addition, it is technically difficult to maintain aqueous
concentrations of gases for toxicity testing. Therefore, in the absence
of measured data the ECOSAR model has been used to calculate the likely
toxicity of buta-1,2-diene to aquatic organisms. The ECOSAR model is a
reliable and appropriate QSAR model to apply to buta-1,2-diene as it is
based on a related chemical dataset that calculates the toxicity of
neutral organic hydrocarbons whose mode of action is non-polar narcosis.
The endpoint calculated here is therefore a reasonable estimate of its
It must be
noted that although the calculated ecotoxicity data are below the
measured water solubility the water solubility test was not done under
representative natural environmental conditions. The high volatility of
this substance will significantly reduce observed concentrations in
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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