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EC number: 209-674-2
CAS number: 590-19-2
accordance with REACH
Annexes VII and VIII column 2 adaptation,
studies on skin sensitisation do not need to be conducted as the
substance is flammable in air at room temperature. No studies have been
conducted on skin sensitisation with 1,2-butadiene but there are no
indications from repeat dose studies on its structural analogue,
1,3-butadiene, that it causes skin sensitisation.
have been conducted on respiratory sensitisation with 1,2-butadiene or
other similar molecules but
there is no data to indicate that 1,2 -butadiene would cause respiratory
There is no
indication that 1,2 -butadiene causes skin or respiratory sensitisation
and therefore, according to the EU and GHS/CLP criteria, 1,2 -butadiene
does not require classification for sensitisation properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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