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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
04 July 1975
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
not specified
Principles of method if other than guideline:
Inhouse SOP (method A.11) validated by Ciba which is comparable to standard guideline.
GLP compliance:
no
Analytical monitoring:
yes
Vehicle:
not specified
Test organisms (species):
other: Rainbow Trout
Details on test organisms:
see below
Test type:
semi-static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
48 h
Hardness:
None
Test temperature:
13
pH:
7.6 to 8.0
Nominal and measured concentrations:
2, 20 and 100 mg/l
Key result
Duration:
48 h
Dose descriptor:
other: TL50
Effect conc.:
12.5 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
other: TL0
Effect conc.:
2 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
other: TL100
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Details on results:
All the fish exposed at 100 mg/l were found dead at 24 h exposure while at 20 mg/l concentaration, 4 and 1 fish were found dead at 24 and 48 h observations, respectively. No mortality was observed at 2 mg/l concentration for the duration of the test.
Validity criteria fulfilled:
yes
Conclusions:
The LD50 of FAT 21015/A in this fish acute toxicity test was determined to be 12.5 mg/L.
Executive summary:

An acute fish toxicity test was performed according to in house SOP (method A.11) validated by Ciba which is comparable to standard guideline i.e. OECD TG 203. Rainbow trout were used in this test. All the fish exposed at 100 mg/l were found dead at 24 h exposure while at 20 mg/l concentaration, 4 and 1 fish were found dead at 24 and 48 h observations, respectively. No mortality was observed at 2 mg/l concentration for the duration of the test. Hence, based on the study results, LD50 of FAT 21015/A was determined to be 12.5 mg/L.

Description of key information

An acute fish toxicity test was performed according to in house SOP (method A.11) validated by Ciba which is comparable to standard guideline i.e. OECD TG 203.Rainbow trout were used in this test.All the fish exposed at 100 mg/l were found dead at 24 h exposure while at 20 mg/l concentaration, 4 and 1 fish were found dead at 24 and 48 h observations, respectively. No mortality was observed at 2 mg/l concentration for the duration of the test. Hence, based on the study results, LD50of FAT 21015/A was determined to be 12.5 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
12.5 mg/L

Additional information