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EC number: 264-885-7
CAS number: 64417-98-7
Skin irritation / corrosion:Based on the test results (in vivo study performed according to OECD guideline 404), yttrium zirconium oxide (a form of zirconium oxide stabilised with yttrium oxide) was determined not to be irritating to the skin of New Zealand White rabbit (Chemical Evaluation and Research Institute, 2000).Eye irritation:Based on the test results obtained with New Zealand White rabbit (in vivo study performed according to OECD guideline 405), yttrium zirconium oxide (a form of zirconium oxide stabilised with yttrium oxide) does not need to be classified as irritating to eyes (Chemical Evaluation and Research Institute, 2000).
Skin irritation / corrosion:
One reliable studiy was identified (Klimisch 2). The study performed by
Chemical Evaluation and Research Institute (2000) is a non-GLP study
performed according to the OECD 404 guideline with minor deviations.
Yttrium zirconium oxide (a form of zirconium oxide stabilised with
yttrium oxide) was determined not to be irritating to New Zealand White
rabbit skin after 4 hours of exposure.
A reliable study was performed with yttrium zirconium oxide (Chemical
Evaluation and Research Institute, 2000) in New Zealand White rabbit
according to OECD guideline 405 with minor deviations. The test
substance was determined to be slightly irritating based on the AFNOR
criteria but the observed effects were fully reversible within 72 hours.
Therefore, it does not need to be classified for eye irritation
according to the rules of the CLP Regulation.
Skin irritation / corrosion:
Based on to the available data and according to the criteria of the CLP
Regulation, this substance should not be classified for skin corrosion /
irritation or for eye irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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