Decanenitrile

Biodegradation in water: screening tests

Administrative data

Endpoint:

biodegradation in water: screening tests

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

There is no data available on biodegradation tests with Caprinonitrile (Decannitrile). In order to classify the substance according to GHS relevant endpoint data available for Dodecannitrile was read-acrossed to Caprinonitrile based on structural similarities. Dodecannitrile is as well as Decanntrile based on aliphatic chains of hydrocarbon atoms. These chains which consist of an even-numbered number of hydrocarbon atoms, are saturated and possess a nitrile-group at its end. Decannitrile consists of 10 hydrocarbon atoms and Dodecannitrile is the next higher analogon with 12 hydrocarbon atoms. Generally it can be assumed that the next lower analogon (Decannitrile) has the same properties as the basic substance (Dodecannitrile). Furthermore it is obvious that if any chemical reaction takes place with those two substances then the nitrile group is the only functional group of this chemicals were a reaction should occur.

Data source

Reference

Reference Type:

other: IUCLID 4 dataset

Title:

IUCLID 4 dataset, Cocosnitrile

Bibliographic source:

European Comission - European Chemicals Bureau

Report date:

2000

Materials and methods

Test guideline

Guideline:

other: Directive 84/449/EEC, C.7 "Biotic degradation - modified MITI test"

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Dodecanenitrile

EC Number:

219-440-1

EC Name:

Dodecanenitrile

Cas Number:

2437-25-4

Molecular formula:

C12H23N

IUPAC Name:

dodecanenitrile

Results and discussion

% Degradation

Parameter:

not specified

Value:

15

Sampling time:

28 d

Applicant's summary and conclusion

Executive summary:

There is no data available on biodegradation test with Caprinonitrile (Decannitrile). In order to classify the substance according to GHS relevant endpoint data available for Dodecannitrile is read-acrossed to Caprinonitrile based on structural similarities (see rationale for reliability).

Available data for Dodecannitrile was found in the IUCLID 4 dataset of the substance Cocosnitrile (CAS: 61789 -53 -5, EC: 263 -066 -1). In this dataset one study on biodegradation with Dodecannitrile (according to Directive 84/449/EEC, C.7 "Biotic degradation - modified MITI test") is mentioned. The result was a degradation of 15 % after 28 days and leads together with the daphia test (see IUCLID chapter 6.1.3) to a classification as "acut. env. tox. cat. 1" (H400) and "chron. env. tox. cat.1" (H410).