Registration Dossier
Registration Dossier
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EC number: 424-590-8 | CAS number: 98298-66-9 CARBONATE DE CHLORO-1-ETHYLE ET ISOPROPYLE
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Test was carried out according to OECD test guideline 401 and in compliance with GLP. Data entered as supplied by ECHA following an inquiry for the same substance.
Data source
Reference
- Reference Type:
- other: study summary provided by ECHA
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: EU B1 - OECD 401
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Chloro-1-ethyl isopropyl carbonate
- EC Number:
- 424-590-8
- EC Name:
- Chloro-1-ethyl isopropyl carbonate
- Cas Number:
- 98298-66-9
- Molecular formula:
- C6H11ClO3
- IUPAC Name:
- 1-chloroethyl propan-2-yl carbonate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- other: corn germ oil
- Doses:
- 2000 mg/kg bw
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 2000 mg/kg bw, Number of animals: 5, Number of deaths: 0
Female: 2000 mg/kg bw, Number of animals: 5, Number of deaths: 0 - Clinical signs:
- other: Signs of toxicity related to dose levels: No clinical signs and no mortality were observed during the study
- Gross pathology:
- No effects on organs
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The LD50 of this substance was found to be >2000 mg/kg, therefore this study demonstrated that the substance is not classified as a acutely toxic via the oral route, according to EU classification criteria (CLP).
- Executive summary:
The LD50 of this substance was found to be >2000 mg/kg, therefore this study demonstrated that the substance is not classified as a acutely toxic via the oral route, according to EU classification criteria (CLP).
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