Registration Dossier
Registration Dossier
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EC number: 940-679-9 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No data on acute toxicity to fish is available for H250 sulphonic acid. Data from LABS Na was used to understand the acute toxicity profile of substance to fish. The toxicity of the analogue substance has been measured experimentally with freshwater fish. The 96 h LC50 value, based on measured concentration, was 1.67 mg a.i./L, with 95% CL 1.58 to 1.77 mg/L.
Key value for chemical safety assessment
Additional information
Benzenesulphonic acid, dimethyl-,mono C14-16-alkyl derivative (H250 sulphonic acid) is a UVCB. Based on structural and functional similarities, data on Benzenesulphonic acid, 4-C10-13-sec-alkyl derivatives (LABS; CAS no: 85536-14-7) being registered under REACH, LABS Na (CAS no: 68411-30-3) being registered under REACH and LAB (CAS no: 67774-74-7) being registered under REACH are suitable as supporting study in case where specific data on the substance is lacking.
To assess the acute toxicity profile of the substance to fish, the data of LABS Na (CAS No: 68411 -30 -3) was used as structural analogue substance. The acute toxicity to fish of LABS Na was determined in USEPA OPPTS 850.1075 (1996) guideline study.
In a 96 h acute toxicity study, Bluegill (Lepomis macrochirus) were exposed to C11.8 LABS Na under static conditions. Nominal concentrations were not specified in the report. Measured concentrations were 79 % of nominal concentrations. The 96 h LC50 value, based on measured concentration, was 1.67 mg a.i./L, with 95% CL 1.58 to 1.77 mg/L.
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