Registration Dossier
Registration Dossier
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EC number: 205-132-4 | CAS number: 134-20-3
Endpoint summary
Administrative data
Description of key information
Hydrolysis:
A 38 days study was conducted to determine the rate of hydrolysis of test chemical at the temperature of 25°C. Test solution was prepared by adding 3ml of test chemical to 300ml of deionized water which was stirred for 12h. Phosphate buffer media was used at pH 5, 7 and 9. Hence, after 38 days the percent recovery of test chemical at pH 5, 7 and 9 was determined to be 100-96%, 97-93% and 97-91%, respectively. Therefore, from the above value, it can be said that the test chemical was non-hydrolysable..
Additional information
Hydrolysis:
Following different studies includes experimental and estimated studies for the test chemical to observe the hydrolysis of test chemical in water.
A 38 days study was conducted to determine the rate of hydrolysis of test chemical at the temperature of 25°C. Test solution was prepared by adding 3ml of test chemical to 300ml of deionized water which was stirred for 12h. Phosphate buffer media was used at pH 5, 7 and 9. Hence, after 38 days the percent recovery of test chemical at pH 5, 7 and 9 was determined to be 100-96%, 97-93% and 97-91%, respectively. Therefore, from the above value, it can be said that the test chemical was non-hydrolysable.
In next study, the base catalyzed second order hydrolysis rate constant of test chemical was determined using a structure estimation method. The second order hydrolysis rate constant of test chemical was determined to be 0.042 L/mol-sec with a half-life value of 5.5 yrs and 200 days at pH 7.0 and 8.0, respectively. Based on the half-life values, it is concluded that the test chemical is not hydrolysable.
Based on the above value, the test chemical determined to be non-hydrolysable.
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