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Diss Factsheets
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EC number: 293-917-2 | CAS number: 91648-55-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Justification for type of information:
- Refer to the Category Approach Justification document provided in IUCLID6 Section 13.
- Qualifier:
- according to guideline
- Guideline:
- other: proposed procedure for toxicity testing with the earthworm Eisenia foetida (Savigny) in artificial soil (USA, 14 d), UBA Berlin 3/1984
- Principles of method if other than guideline:
- mortality of Eisenia fetida in artificial soil spiked with test substance
- GLP compliance:
- not specified
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Total exposure duration:
- 14 d
- Reference substance (positive control):
- not specified
- Duration:
- 14 d
- Dose descriptor:
- EC0
- Effect conc.:
- > 1 000 mg/kg soil dw
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Refer to the Category Approach Justification document provided in IUCLID6 Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Duration:
- 14 d
- Dose descriptor:
- EC0
- Effect conc.:
- > 1 000 mg/kg soil dw
- Conc. based on:
- act. ingr.
- Basis for effect:
- mortality
Referenceopen allclose all
Description of key information
14d EC50 (Eisenia fetida, mortality) > 1000 mg/soil d.w. (nominal concentration, UBA Berlin 3/1984)
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 1 000 mg/kg soil dw
Additional information
In accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read-across to another structurally related substance was conducted. Read-across data available for C16-18AS Na (CAS 68955-20-4) were used, since toxicity of alkyl sulfates is dependent on the carbon chain length.
One reliable short-term study with Eisenia fetida is available for C16-18AS Na (CAS 68955-20-4, Steber 1988). The study followed the procedure for toxicity testing with the earthworm Eisenia fetida (Savigny) in artificial soil (USA, 14 d), UBA Berlin 3/1984. Earthworms were exposed to the test substance for 14 days in artificial soil. The 14-day EC0 value based on mortality was above 1000 mg a.i./kg soil d.w.
Besides, the Equilibrium Partitioning Method is sufficient to calculate the PNECs values for the terrestrial compartment. The substance exhibits an adsorption coefficient (log Koc) below 5 and is readily biodegradable. In case of exposure to soil, the substance is expected to rapidly degrade, thus the hazard to terrestrial organisms is negligible. Hence, the Equilibrium Partitioning Method is sufficient to calculate the PNECs values for the terrestrial compartment according to the “Guidance on information requirements and chemical safety assessment Chapter R.7c: Endpoint specific guidance”, Section 7.11.6 Integrated Testing Strategy for Effects on Terrestrial Organisms (ECHA 2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.