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EC number: 944-989-5
CAS number: 2156592-46-8
An acute oral toxicity test was carried out
on a group of 10 rats (5 male and 5 female) using Cosmacol ECI. The test
material was administered at a dose of 5000 mg/kg oral by gavage. During
the study the animals were observed daily for 14 days (5 out of 7) for
signs of possible toxic symptoms and mortality. Body weight was noted
weekly. At the end of the study necropsy was performed on all animals.
None of the animals died during the course
of the study, no clincial symptoms were observed that could be related
to treatment, the body weight gain was normal for the species and
strain. At necropsy the animals showed no pathological symptoms or
abnormalities ante- and post-mortem.
The test material Cosmacol ECI did not
provoke toxic effects under the experimental conditions described and
the LD50 was judged to be greater than 5000 mg/kg b.w.
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