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EC number: 810-298-1
CAS number: 194934-66-2
Table1 Individual Clinical
Observations and Mortality Data -300mg/kg
Dose Level mg/kg
Animal Number and Sex
Effects Noted After Dosing(Hours)
Effects Noted During Period After Dosing(Days)
0= No signs of systemic
Table2 Individual Body
Weights and Body Weight Changes -300mg/kg
Animal Numberand Sex
Body Weight (g) at Day
Body Weight Gain (g)During Week
Table3 Individual Necropsy
Findings -300 mg/kg
Time of Death
Killed Day 14
No abnormalities detected
Table4 Individual Clinical
Observations and Mortality Data -2000mg/kg
0= No signs of systemic toxicity
Table5 Individual Body Weights
and Body Weight Changes -2000mg/kg
Body Weight Gain (g) During Week
Table6 Individual Necropsy
The study was performed to assess the
acute oral toxicity of the test item in the Wistar strain rat.
Following a sighting test at dose
levels of 300 mg/kg and 2000 mg/kg, a further group of four fasted
females was given a single oral dose of test item at a dose level of
2000 mg/kg body weight. Clinical signs and body weight development were
monitored during the study. All animals were subjected to gross necropsy.
were no deaths.
were no signs of systemic toxicity.
animals showed expected gains in body weight.
abnormalities were noted at necropsy.
The acute oral median lethal dose (LD50)
of the test item in the female Wistar strain rat was estimated to be
greater than 2000 mg/kg body weight (Globally Harmonized Classification
System - Unclassified).
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