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EC number: 267-122-6
CAS number: 67801-01-8
As can be seen above, the percutaneous absorption of D & C Red No. 9
through human skin is very low. With all four vehicles, total absorption
was less than 0.1% of the applied dose and the maximum flux rate
achieved was less than 0.1 mug/cm2/24 hours. Due to the small number of
experiments run, it was impossible to determine whether the apparent
differences between vehicles were significant.
The vast majority of the unabsorbed material remained on the surface of
the skin and was found in the skin wash. This amount varied from 85-103
%. Very little colorant was found in the epidermis or dermis, less than
0.3% in all cases. Total drug recovery averaged 83-103% of the applied
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