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EC number: 413-110-2
CAS number: 135861-56-2
Maximum concentration not causing irritation effects: 10% (w/v)
The substance was tested in two GLP studies (Pharmakon Europe,1993 and
Safepharm Laboratories,1998) in absolute ethanol or arachis oil,
respectively, using the guinea–pig Magnusson & Kligman Maximisation
Test, with single intradermal (0.1% w/w or 0.5% w/w respectively) and
topical (0.1% w/w or 25% w/w respectively) induction administrations one
week apart, and a single challenge application (50% w/w or 5 and 10% w/w
respectively) two weeks later. There were no positive reactions observed
to challenge with the test material in any test or vehicle control
No study data are available for respiratory sensitisation. In the
absence of skin sensitisation, respiratory sensitisation is not expected
to occur. .
The available animal test data are reliable and suitable for
classification purposes under regulation 1272/2008. The substance is not
therefore classified for skin sensitisation under EU CLP criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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