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EC number: 425-220-8
CAS number: 5945-33-5
Oral:LD50: >2 000 mg/kg for rat (limit test) (OECD TG401)Dermal:LD50: >2 000 mg/kg for rat (limit test) (OECD TG402)
The acute oral and dermal toxicity tests (according to OECD TG 401 and
402) were well investigated by Allen in1997, the results indicated the
test material has very low oral and dermal toxicity in rats. OECD TG 401
was deleted in 2002 due to animal welfare reasons, however, the validity
of the results which accomplished by TG 401 should be confirmed.
According to the nature of the substance and the likely routes of human
exposure, the acute inhalation toxicity study might not be considered.
Moreover, the laboratory facilities which complying with OECD Principles
of Good Laboratory Practice were utilized in order to ensure the
consistency and reliability. These two studies were utilized as key
studies in substance acute toxicity evaluation due to their high
adequation, reliability and relevance to this element.
According to the existing studies on acute oral and dermal toxicity
tests (LD50 > 2000 mg/kg bw) in rats, which provide sound conclusive
evidence that the substance (CAS:5945-33-5 ) does not require
classification as set of risk phrases for these endpoints.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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