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EC number: 425-220-8
CAS number: 5945-33-5
A test for ready biodegradability conducted according to the Modified
MITI (OECD Test Guideline 301C) indicated that the chemical only very
slowly degraded under the conditions of the test (Iwami S, 1994). The
result of this test indicates that the BDP is not readily biodegradable.
The compound has a large Koc (log Koc > 4.53), indicating strong
affinity for the organic component of soils and sediments, and low
mobility in these media. The log of the adsorption coefficient
(Koc) of BDP was also determined to be higher than 6.87 using batch
equilibrium method (OECD TG 106).
The high log Pow (> 6), relatively low molecular weight (693 g/mol) and
low water solubility (0.4 mg/L), which were all used to estimate the
BCFs of BDP, indicates that the BCFs were lower than 250, and BDP was
not likely to cause bioaccumulation.
Furthermore, BCF was determined via a Bioconcentration Test (Semi-Static
System) to Zebra-fish (Brachydanio rerio) in accordance with OECD Test
Guideline 305.The study was conducted under semi-static conditions
with the nominal concentration of 0.4 mg/L and solvent control for a
period of 33 days. 250 test fish were used for each treatment and
equally divided into 10 test containers. The test solution was renewed
once every two days. During the exposure time, the mortality, number of
abnormal fish and abnormal behavior of fish was observed and recorded
once a day. The water sample and fish sample were taken to analyze the
concentration of the test substance (BDP). The bioconcentration factor
(BCF) value was calculated as the ratio (as BCFss) of concentration in
the fish (Cf) and in the water (Cw) at the apparent steady-state. BDP
was stable under test condition.During the test, based on the nominal
concentration of 0.4 mg/L, the mean measured concentration of BDP test
solution was 0.37 mg/Land standard deviation was 0.04.The steady state
determined to be 5, which therefore showed BDP is not bioaccumulative in
Zebra fish (Brachydanio rerio).
Hydrolytic degradation of the compound was studied as a function of pH
by incubating stoppered flasks containing (nominally) 0.25 mg/L in
buffer solutions at pH 4, 7 and 9 for 5 days. The concentration of the
compound in the solutions was determined using HPLC at various times
over the 5 day (120 hour) test period. Very little degradation was
observed in any of the buffers over the 5 day test period, with the
maximum loss of 5% of initial concentration observed in the pH 9 buffer.
These data indicate that the phosphate ester linkages within the
molecules are stable to hydrolysis at 50°C. The small extent of observed
degradation extrapolated to 25 °C indicates a half life of greater than
1 year at environmental pH 4-9.
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