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Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 15, 1991
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report date:
1991

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 116 (Fat Solubility of Solid and Liquid Substances)
Qualifier:
according to guideline
Guideline:
other: EEC guideline (European Economic Community (EEC), EEC Directive 841449 EEC, Annex, part A: Methods for the determination of physico-chemical properties, A.7:"Fat solubility", EEC Publication No.L251, September 1984
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
α-trimethylsilanyl-ω-trimethylsiloxypoly[oxy(methyl-3-(2-(2-methoxypropoxy)propoxy)propylsilanediyl]-co-oxy(dimethylsilane))
EC Number:
406-420-4
EC Name:
α-trimethylsilanyl-ω-trimethylsiloxypoly[oxy(methyl-3-(2-(2-methoxypropoxy)propoxy)propylsilanediyl]-co-oxy(dimethylsilane))
Cas Number:
69430-40-6
Molecular formula:
Unspecified example: C18.3H46.8O5.8Si4.1
IUPAC Name:
α-trimethylsilanyl-ω-trimethylsiloxypoly[oxy(methyl-3-(2-(2-methoxypropoxy)propoxy)propylsilanediyl]-co-oxy(dimethylsilane))
Details on test material:
- Name of test material (as cited in study report): DC 5067
- Substance type: Reaction mass (mixture)
- Physical state: Liquid
- Analytical purity: > 99%
- Lot/batch No.: AB 090122
- Expiration date of the lot/batch: December 1, 1991
- Stability under test conditions: Stable
- Storage condition of test material: In the original container at room temperature in the dark
- Other:

Results and discussion

Solubility in organic solvents / fat solubility
Medium:
standard fat
Remarks:
HB 307
Solubility:
>= 0.01 - <= 100 vol%
Temp.:
37 °C
Test substance stable:
yes

Applicant's summary and conclusion

Conclusions:
DC 5067 was determined to be miscible with standard fat HB 307.
Executive summary:

Because.in the preliminary test the test substance appeared to be miscible with standard fat HB 307 in a 1:l ratio (v/v), the main study was not performed. Alternatively, the fat miscibility at different ratio's was tested. The test substance DC 5067 was determined to be miscible with standard fat HB 307. At different ratios "test substance/standard fat (vlv)", ranging between 100 and 0.01, clear, light brown mixtures were observed. The temperature of measurement was 37.0 +- 0.5°C.