Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation / corrosion, other
Remarks:
in vivo study
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2001
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001
Report date:
2001

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Bundesministerium für Land- und Forstwirtschaft Umwelt und Wasserwirtschaft, Vienna, Austria

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
439-590-3
EC Name:
-
Cas Number:
12158-75-7
Molecular formula:
Hill: Cu2(OH)3NO3 CAS:
IUPAC Name:
copper trihydroxynitrate
Details on test material:
CAS# 12158-75-7, Batch 060248

Test animals

Species:
rabbit
Strain:
New Zealand White

Test system

Type of coverage:
semiocclusive
Preparation of test site:
shaved
Vehicle:
water
Controls:
no
Duration of treatment / exposure:
4 h
Observation period:
72 h
Number of animals:
3 female

Results and discussion

In vivo

Resultsopen allclose all
Irritation parameter:
erythema score
Basis:
other: all
Time point:
other: all
Score:
0
Max. score:
0
Reversibility:
other: n.a.
Irritation parameter:
edema score
Basis:
other: all
Time point:
other: all
Score:
0
Max. score:
0
Reversibility:
other: n.a.
Other effects:
no effects

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: OECD GHS
Conclusions:
no general toxic effects was observed