Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: - | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2001
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Bundesministerium für Land- und Forstwirtschaft Umwelt und Wasserwirtschaft, Vienna, Austria
- Test type:
- acute toxic class method
Test material
- Reference substance name:
- -
- EC Number:
- 439-590-3
- EC Name:
- -
- Cas Number:
- 12158-75-7
- Molecular formula:
- Hill: Cu2(OH)3NO3 CAS:
- IUPAC Name:
- copper trihydroxynitrate
- Details on test material:
- CAS# 12158-75-7, Batch 060248
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: Crl:CD(SD)IGS BR
- Sex:
- male/female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- not specified
- Doses:
- 200 (3xM, 3xF), 2000 (3xM)
- No. of animals per sex per dose:
- 200 (3xM, 3xF), 2000 (3xM)
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- > 500 - < 1 000 mg/kg bw
Any other information on results incl. tables
Dose |
Sex |
Animal No. |
Exposed |
Affected |
deceased |
Time of Death |
200 |
M |
71-73 |
3 |
0 |
0 |
survived |
200 |
F |
76-78 |
3 |
0 |
0 |
Survived |
2000 |
M |
81 82 83 |
3
|
3 |
2 |
2 – 4 h Survived 2-4 h |
Applicant's summary and conclusion
- Interpretation of results:
- Category 4 based on GHS criteria
- Remarks:
- Migrated information
- Conclusions:
- LD_{50, rat} is estimated higer than 500 but lower then 1000 mg / kg bw
67/548: harmful
1272/2008: acut tox cat. 4
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