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EC number: 946-788-8
CAS number: -
As the observations time were only at 24
and 72 h, for mean calculations of 24/48/72 h it was used the worst case
approach using the higher score at 48 h.
The skin irritation test was performed to
rabbit skin according to an internal method: a single dose was tested on
the skin of six rabbits. 0.5 g of test substance was applied to intact
and wound skin of each animal using a 25 cm2 sticking
plaster. The degree of irritation/corrosion was read and scored for
oedema and erythema reactions at intervals of 24 and 72 hours. The
erythema and the oedema scores were calculated following the mean values
after 24/48/72 h. For the scores at 48 h the greater value observed
during the test was considered, as no observation was performed at this
time-point. The erythema and oedema scores (mean values 24/48/72 hours)
were 0 in all animals.
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