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EC number: 248-607-1
CAS number: 27689-12-9
mutagenic potential of the test article was evaluated in the Bacterial
Reverse Mutation Assay with S. typhimurium strains TA98, TA100, TA1535,
and TA1537 and E. coli strain WP2 uvrA in the presence and absence of a
metabolic activation system (Aroclor induced - S9 mix). The study was
performed in compliance with FDA GLP 21 CFR 58 and OECD GLP
C(97)186/Final. The test method was based on OECD No. 471 (1997). The
test article was diluted in DMSO and dosed at 15, 50, 150, 500, 1500 and
5000 ug/plate. Strain specific controls and vehicle controls were also
prepared. Separate experiments were performed in the presence and
absence of metabolic activation. Precipitation was noted at 500 or 1500
mg/plate. No toxicity was observed. No mutagenic responses were
observed in any strain in the presence or absence of metabolic
activation. Based on the results of the test, the test article was not
mutagenic in the Bacterial Reverse Mutation Assay in the presence or
absence of metabolic activation.
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