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EC number: 935-411-2
CAS number: -
The objective of this study was to assess the toxicity of the test item when administered in a single dose to female rats at one defined dosage. The study was carried out in compliance with the guidelines described in OECD No.423 (2001) "Acute Oral Toxicity, Acute Toxic Class Method".
Reaction products of 4,4'-isopropylidenediphenol, ethoxylated and methacrylic acid was administered by oral gavage to two consecutive groups of three female Wistar Han rats at 2000 mg/kg body weight. Animals were subjected to daily observations and weekly determination of body weight. Macroscopic examination was performed after terminal sacrifice (Day 15).
No mortality occurred. Restless behavior, hunched posture and/or piloerection were noted for the animals between Days 1 and 3. The mean body weight gain shown by the animals over the study period was considered to be normal. No abnormalities were found at macroscopic post mortem examination of the animals.
The oral LD0 value of Reaction products of 4,4'-isopropylidenediphenol, ethoxylated and methacrylic acid in Wistar Han rats was established to exceed 2000 mg/kg body weight.
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