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EC number: 271-085-1
CAS number: 68515-43-5
The No Observed Adverse Effect level (NOAEL) for males is considered to
be a concentration of 0.1 % in the diet, corresponding to a mean intake
of 79.6 mg/kg bw/day based on hepatotoxic effects shown as histological
changes in the liver and effects on liver enzymes. For females the NOAEL
is considered to be 0.3 %, corresponding to a mean intake of 303.9 mg/kg
bw/day on the basis of increased liver and kidney weights, effects on
liver enzymes and haematological parameters.
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