Reaction products of furan-2,5-dione and octadec-1-ene

Endpoint summary

Additional information

Aquatic toxicity testing by read-across from an analogue substance included short-term toxicity testing in a freshwater fish (golden orfe, Leuciscus idus) and a freshwater aquatic invertebrate (water flea, Daphnia magna), and a growth inhibition assay on a freshwater alga (Desmodesmus subspicatus, formerly called Scenedesmus subspicata). The most sensitive aquatic trophic level may be fish, with a reported 96-h EC₅₀ of > 10 mg/L; a 48-h EL₅₀ in aquatic invertebrates was reported as 36.3 mg/L and the 72-h E_rL₅₀ in algae was reported as 85.1 mg/L. In addition, a read-across substance was tested for cell multiplication inhibition test on the bacterium Pseudomonas putida, from which a 16-h NOEC of ≥ 8 mg/L was reported. Long-term testing in fish and invertebrates was not conducted; the substance undergoes rapid hydrolysis, is soluble in water and has been shown to be rapidly degraded in the environment. The results of the chemical safety assessment showed that the risk characterization ratios for surface water are all below one. Therefore, long-term aquatic toxicity testing was not indicated.