Iron(1+), chloro[dimethyl 9,9-dihydroxy-3-methyl-2,4-di(2-pyridinyl-kN)-7-[(2-pyridinyl-kN)methyl]-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarboxylate-kN3,kN7]-, chloride

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 2004-04-21 to 2004-06-23

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2004

Report date:

2004

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

effusion method: vapour pressure balance

Test material

Test material information

Constituent 1

Reference substance name:

1,5-dimethyl 3-methyl-9-oxo-2,4-bis(pyridin-2-yl)-7-[(pyridin-2-yl)methyl]-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarboxylate dichloroiron hydrate

EC Number:

610-388-9

Cas Number:

478945-46-9

Molecular formula:

C28H31N5O6FeCl2

IUPAC Name:

1,5-dimethyl 3-methyl-9-oxo-2,4-bis(pyridin-2-yl)-7-[(pyridin-2-yl)methyl]-3,7-diazabicyclo[3.3.1]nonane-1,5-dicarboxylate dichloroiron hydrate

Test material form:

solid: particulate/powder

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: S2539801
- Expiration date of the lot/batch:
- Purity test date: 2004-11-12

RADIOLABELLING INFORMATION (if applicable) no

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
ambient/dark

TREATMENT OF TEST MATERIAL PRIOR TO TESTING: no

Results and discussion

Vapour pressure

Key result

Temp.:

25 °C

Vapour pressure:

0 Pa

Any other information on results incl. tables

Summary of results:

Run  Log10[Vp(25°C)]  1  -6.051  2  -5.788  3  -4.794  4  -5.203  5  -4.816  6  -5.023  Mean  -5.279  Vapour pressure  5.3E-6 Pa

It was evident that there was a poor correlation both within each run and between runs. This was due to the low mass difference readings observed, being close to noise level. There is however, within each run, a consistent general increase of vapour pressure with temperature and so it was considered inapropriate to assign a maximum (least negative) slope to extrapolate a worst case limit value.

It was considered more appropriate to accumulate data so that the extrapolated values average can tend towards the true value. Due to the low level of the extrapolated values, the correlation between readings was considered sufficient for the purpose of notification.

The test material darkened slghtly under the conditions used in the determination.

Applicant's summary and conclusion

Conclusions:

The vapour pressure of the test material has been determined to be 5.3E-6 pa at 25°C.

Executive summary:

The purpose of the test was to determine the vapour pressure of the test item, according to the A4 method and following GLP. A vapour pressure balance was used. The vapour pressure of the test material has been determined to be 5.3E-6 pa at 25°C.