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EC number: 267-008-6 | CAS number: 67762-27-0 This substance is identified by SDA Substance Name: C16-C18 alkyl alcohol and SDA Reporting Number: 19-060-00.
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial plants: long-term
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction: US EPA accepted QSAR method for chemicals properties assessment.
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR
- Principles of method if other than guideline:
- EPI Suite v 4.1/ECOSARv1.00
- GLP compliance:
- no
- Remarks:
- not applicable. QSAR model
- Analytical monitoring:
- not required
- Vehicle:
- no
- Species:
- other: Terrestrial plants,QSAR model
- Plant group:
- other: QSAR model
- Details on test organisms:
- no further information
- Test type:
- other: QSAR
- Study type:
- other: QSAR
- Substrate type:
- other: QSAR
- Limit test:
- no
- Total exposure duration:
- 30 d
- Test temperature:
- not applicable. QSAR model
- pH:
- not applicable. QSAR model
- Moisture:
- not applicable. QSAR model
- Details on test conditions:
- CAS Number: 67762-27-0
SMILES : CCCCCCCCCCCCCCCCO
CHEM : Alcohols, C16-18
MOL FOR: C16 H34 O1
MOL WT : 242.45
Log Kow: 6.73 (KowWin estimate)
Wat Sol: 0.0412 mg/L (experimental database) - Reference substance (positive control):
- no
- Species:
- other: Terrestrial plants,QSAR model
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.054 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: (Q)SAR prediction
- Remarks on result:
- other: non-toxic at the limit of solubility, as determined by (Q)SAR
- Species:
- other: Terrestrial plants,QSAR model
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 540 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: (Q)SAR prediction
- Remarks on result:
- other: Predicted, at water solubility loading rates of 1000 mg/L
- Species:
- other: Terrestrial plants,QSAR model
- Duration:
- 30 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.045 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: (Q)SAR prediction
- Remarks on result:
- other: non-toxic at the limit of solubility, as determined by (Q)SAR
- Species:
- other: Terrestrial plants,QSAR model
- Duration:
- 30 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 450 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: (Q)SAR prediction
- Remarks on result:
- other: Predicted, at water solubility loading rates of 1000 mg/L
- Details on results:
- The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 0.045 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 valuewould to be 0.054 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
A 96 h LC50 value of 0.054 mg/L has been calculated for the effects of the test substance on the mortality of the terrestrial plants.This result signifies that the test substance is not expected to be toxic at the limit of solubility. This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and LC50 is >LoS.
A reliable 96 h LC50 value of 540 mg/L has been calculated for the effects of the test substance towards terrestrial plants.. Therefore the test substance has been predicted to be non toxic at the limit of solubility, so the LC50 is 0.054 mg/L. Predicted to be non-toxic at the limit of solubility.
A NOEC value of 0.045 mg/L has been calculated for the effects of the test substance on the mortality of the terrestrial plants.. This result signifies that the test substance is not expected to be toxic at the limit of solubility. This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and NOEC is >LoS.
A reliable NOEC value of 450 mg/L has been calculated for the effects of the test substance towards terrestrial plants.. Therefore the test substance has been predicted to be non toxic at the limit of solubility, so the NOEC is 0.045 mg/L. Predicted to be non-toxic at the limit of solubility.
The water solubility of the Alcohols, C16-18 is 0.0412 mg/l at 25 degC (experimental database). This is about 10000 times the water solubility of the test substance. - Validity criteria fulfilled:
- yes
- Remarks:
- US EPA accepted QSAR method for chemicals properties assessment.
- Conclusions:
- The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 0.045 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 valuewould to be 0.054 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
A 96 h LC50 value of 0.054 mg/L has been calculated for the effects of the test substance on the mortality of the terrestrial plants.This result signifies that the test substance is not expected to be toxic at the limit of solubility. This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and LC50 is >LoS.
A reliable 96 h LC50 value of 540 mg/L has been calculated for the effects of the test substance towards terrestrial plants.. Therefore the test substance has been predicted to be non toxic at the limit of solubility, so the LC50 is 0.054 mg/L. Predicted to be non-toxic at the limit of solubility.
A NOEC value of 0.045 mg/L has been calculated for the effects of the test substance on the mortality of the terrestrial plants.. This result signifies that the test substance is not expected to be toxic at the limit of solubility. This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and NOEC is >LoS.
A reliable NOEC value of 450 mg/L has been calculated for the effects of the test substance towards terrestrial plants.. Therefore the test substance has been predicted to be non toxic at the limit of solubility, so the NOEC is 0.045 mg/L. Predicted to be non-toxic at the limit of solubility.
The water solubility of the Alcohols, C16-18 is 0.0412 mg/l at 25 degC (experimental database). This is about 10000 times the water solubility of the test substance. - Executive summary:
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 0.045 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 valuewould to be 0.054 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
A 96 h LC50 value of 0.054 mg/L has been calculated for the effects of the test substance on the mortality of the terrestrial plants.This result signifies that the test substance is not expected to be toxic at the limit of solubility. This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and LC50 is >LoS.
A reliable 96 h LC50 value of 540 mg/L has been calculated for the effects of the test substance towards terrestrial plants.. Therefore the test substance has been predicted to be non toxic at the limit of solubility, so the LC50 is 0.054 mg/L. Predicted to be non-toxic at the limit of solubility.
A NOEC value of 0.045 mg/L has been calculated for the effects of the test substance on the mortality of the terrestrial plants.. This result signifies that the test substance is not expected to be toxic at the limit of solubility. This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and NOEC is >LoS.
A reliable NOEC value of 450 mg/L has been calculated for the effects of the test substance towards terrestrial plants.. Therefore the test substance has been predicted to be non toxic at the limit of solubility, so the NOEC is 0.045 mg/L. Predicted to be non-toxic at the limit of solubility.
The water solubility of the Alcohols, C16-18 is 0.0412 mg/l at 25 degC (experimental database). This is about 10000 times the water solubility of the test substance.
- Endpoint:
- toxicity to terrestrial plants: long-term
- Type of information:
- other: published data
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- according to guideline
- Guideline:
- other: Verfahrensvorschlag 'Phytotoxizitaetstest an einer monokotylen Pflanzenart (Avena sativa L.) und einer dikotylen Pflanzenart (Brassica rapa ssp. rapa (DC) Metzg.) (EC50, 14 Tage), Umweltbundesamt, 3/1984.
- Deviations:
- not specified
- Principles of method if other than guideline:
- 14-d phytotoxicity test on seedling emergence
- GLP compliance:
- not specified
- Analytical monitoring:
- no
- Vehicle:
- no
- Species:
- Brassica rapa
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- Details on test organisms
Details on test organisms
- Common name: field mustard
- Plant family: Brassicaceae - Test type:
- seedling emergence toxicity test
- Study type:
- laboratory study
- Substrate type:
- artificial soil
- Limit test:
- no
- Total exposure duration:
- 14 d
- Reference substance (positive control):
- not specified
- Species:
- Brassica rapa
- Duration:
- 14 d
- Dose descriptor:
- EC0
- Effect conc.:
- > 1 000 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Validity criteria fulfilled:
- not specified
- Conclusions:
- In the chronic 14-day test on seedling emergence of brassica rapa no toxic effects could be observed. EC0 was>1000 mg/kg soil dw
- Executive summary:
In the chronic 14-day test on seedling emergence of brassica rapa according to 'Verfahrensvorschlag Phytotoxizitaetstest an einer monokotylen Pflanzenart (Avena sativa L.) und einer dikotylen Pflanzenart (Brassica rapa ssp. rapa (DC) Metzg.) (EC50, 14 Tage), Umweltbundesamt, 3/1984.' no toxic effects could be observed.
Referenceopen allclose all
Overview of QSARs estimations on toxicity of
Alcohols, C16-18
to terrestrial plants
Method
|
Results |
Remarks |
Reference |
QSAR estimate |
Terrestrial plants ,96-hrEC50 = 0.054 mg/L (ppm) Terrestrial plants, 30-day, ChV (chronic value) =0.045 mg/L (ppm)
|
Reliable with restrictions, QSAR estimated data |
ECOSAR Program (v1.00) |
Terrestrial plants ,96-hrEC50 = 0.054 mg/L (ppm)
Terrestrial plants, 30-day, ChV (chronic value) =0.045 mg/L (ppm)
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
Description of key information
In the chronic 14-day test on seedling emergence of brassica rapa no toxic effects could be observed. EC0 was>1000 mg/kg soil dw
Key value for chemical safety assessment
- Short-term EC50 or LC50 for terrestrial plants:
- 5 000 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for terrestrial plants:
- 1 000 mg/kg soil dw
Additional information
In the chronic 14-day test on seedling emergence of brassica rapa no toxic effects could be observed. EC0 was>1000 mg/kg soil dw
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Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
