Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
Valid acute studies based on international guidelines are available for the three aquatic trophic levels (algae, aquatic invertebrates and fish). Among all data available, a toxic effect was observed for the three aquatic trophic levels. The fish, Danio rerio, is the most sensitive species with a 96h-LC50 value at 11.3 mg/L based on analytically confirmed nominal concentrations. For the algae, Pseudokirchneriella subcapitata, the 72h- ErC50, 72h-ErC10 and 72h-NOECr values based on growth rate are 55, 13 and 3.2 mg/L, respectively, based on time-weighted average concentrations. As the ratio NOEC/LOEC is higher than 3.2, the NOECr for the algae test is considered unacceptable and the 72h-ErC10 has been used as critical value. For the aquatic invertebrates, Daphnia magna, the 48h-EC50 value was determined to be 21 mg/L based on analytically confirmed nominal concentrations. In addition, the registered substance was not toxic to activated sludge of a municipal sewage treatment plant up to the nominal concentration of 100 mg/L.
Additional information
Although not requested under REACH Annex VII, the vertebrate acute fish study was performed to comply with worldwide regulations.
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