Registration Dossier
Registration Dossier
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EC number: 246-836-1 | CAS number: 25321-14-6
Repeated dose toxicity: other routes
Administrative data
- Endpoint:
- repeated dose toxicity: other route
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
Data source
Reference
- Title:
- No information
- Author:
- Shils M.E., L.J. Goldwater, Arch. Ind. Hyg. Occup. Med. 8,|262-267 (1957)
Materials and methods
- Principles of method if other than guideline:
- Method: other: see remarks
- GLP compliance:
- no
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- 2.4-DNT (no further information) in corn oil
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sherman
- Sex:
- male
Administration / exposure
- Route of administration:
- intraperitoneal
- Duration of treatment / exposure:
- 43 d
- Frequency of treatment:
- once daily
Doses / concentrations
- Remarks:
- Doses / Concentrations:
10 mg/100 g bw in corn oil
- Control animals:
- yes, concurrent vehicle
- Details on study design:
- Post-exposure period: no
Results and discussion
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
RS-Freetext:
irrespective of diet: reduced growth, anemia, but no effect
on white blood cell count
mortality: 0/9 (D1,D3, D4), 9/10 (D2)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
