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EC number: 202-795-1
CAS number: 99-86-5
Table 1. Distribution of mortality
Deaths/ number of animals
In this study, an on oral acute toxicity was conducted in the rat using
Ten rats per treatment were exposed to the following doses: 1.05, 1.31,
1.64, 2.05 and 5 g/kg. Rats were observed for 14 days.
No clinical findings and deaths occurred in the lowest tested dose (1.05
g/kg). Lethargy was observed on the day of dosing in rats dosed at 1.31,
1.64, 2.05 and 5 g/kg. The rats dosed at 2.05 and 5 g/kg exhibited loss
of righting reflex and piloerection.
The exposure to the middle doses (1.31 and 1.64 g/kg) caused 40% of
death. 80% of death animals were found at 2.05 g/kg within 10 days after
a single exposure.
The highest dose caused 100% of death after 24 hrs. (8 deaths) and 48
hrs (2 deaths), respectively.
Based on the results the LD50 was calculated to be 1.68 g/kg (1.46 -
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