Registration Dossier
Registration Dossier
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EC number: 203-687-7 | CAS number: 109-61-5
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish
Parent compound propyl chloroformate (CAS 109-61-5): BASF AG, 1998, GLP, OECD 203, Danio rerio, static, 96 h LC50 = 3.16 mg/L (nominal, not analytically verified).
Based on this result, propyl chloroformate is considered acutely toxic to fish
Hydrolysis product propanol (CAS 71-23-8): Brooke et al., 1984, APHA, Pimephales promelas, flow-through, 96 h LC50 = 4480/4630 mg/L (test 1/test 2, nominal, analytically verified).
Based on this result, the hydrolysis product propanol is considered acutely not harmful to fish
Long-term toxicity to fish
Not required under this tonnage band
Short-term toxicity to aquatic invertebrates
Parent compound propyl chloroformate (CAS 109-61-5): no data available
Hydrolysis product propanol (CAS 71-23-8): Kühn et al., 1989, DIN38412,
part 11, Daphnia magna, 48 h EC50 = 3644 mg/L (nominal, not
analytically verified).
Based on these results, the hydrolysis product propanol is considered to be acutely not harmful to aquatic invertebrates.
Long-term toxicity to aquatic invertebrates
Not required under this tonnage band
Growth inhibition to aquatic algae
Parent compound propyl chloroformate (CAS 109-61-5): no data available
Hydrolysis product propanol (CAS 71-23-8): Slooff et al., 1983, 96 h growth inhibition test, Pseudokirchneriella subcapitata (formerly: Selenastrum capricornutum), 96 h EC50 > 2000 mg/L, 96 h NOEC = 2000 mg/L (nominal, not analytically verified)
Based on these result, propanol is considered to be acutely not harmful to aquatic algae.
Toxicity to microorganisms
Parent compound propyl chloroformate (CAS 109-61-5): no data available
Hydrolysis product propanol (CAS 71-23-8): Kleĉka et al., 1985, OECD TG
209, activated sludge, 3 h EC50 > 1000 mg/L
Based on this result, an inhibition of the degradation activity of activated sludge is not expected when introduced to biological treatment plants in appropriate low concentrations.
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