Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-687-7 | CAS number: 109-61-5
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Propyl chloroformate (CAS 109-61-5) rapidly hydrolyses in contact with water to form propanol (CAS 71-23-8), hydrogen chloride (CAS 7647-01-0) and carbon dioxide (CAS 124-38-9). Due to this rapid hydrolysis, the assessment of the PBT/vPvB properties of the parent compound is considered to be of low relevance. As the PBT/vPvB criteria of Annex XIII do not apply to inorganic substances, only the hydrolysis product propanol is considered.
Propanol was determined to be readily biodegradable. Therefore, the substance does not fulfill the screening criteria for P/vP.
The estimated log Kow of propyl chloroformate (log Kow = 1.12) as well as the experimental log Kow of propanol (log Kow = 0.2) indicate that significant bioaccumulation in organisms is not to be expected. It can be concluded that the substance is not B/vB.
Chronic toxicity data are available for algae only. Acute toxicity data are available for fish, daphnids and algae. The lowest chronic effect value is significantly greater than 0.01 mg/L (96 h NOEC = 2000 mg/L; Slooff et al., 1983). In addition, all available acute toxicity values (LC/EC50) are clearly greater than 0.01 mg/L (for details see IUCLID chapter 6.1). The substance is concluded to be not T.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
