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EC number: 943-030-8
CAS number: -
LC50, 96h, Oncorhynchus mykiss = 509 mg/l (nominal)
Two studies were conducted on short-term
toxicity to rainbow trout (Oncorhynchus mykiss) on the analogue
substance. The first study (according to EU Method C.1) exposed groups
of 10 animals to test item concentrations of 300, 350, 450, 500, 600 and
800 mg/l in reconstituted water for 96 hours, plus a control group of 10
animals were exposed to reconstituted water alone. Measured
concentrations fell within 97.7 % to 108.3 % of nominal test item
concentrations. A dose-response relationship with mortality was evident.
The 96-hour LC50 of the test item was calculated to be 509.1 mg/l
(nominal concentrations) using the LOGIT Model at 95 % confidence limits
based on mortality.
The second study (according to the OECD
Guideline 203, 1981) was a limit test according to the OECD Guideline
203 (1981) whereby 10 rainbow trout were exposed to 100 mg/l test item
for 96 hours in a limit test, and a negative control group of 10 rainbow
trout were exposed to test medium alone. Measured test item
concentrations fell between 101.0 and 103.5 % of nominal concentrations.
As no mortality was observed, the 96-hour LC50is therefore
higher than 100 mg/l (nominal concentration).
Based on the read across considerations
same results apply to the target substance and the LD50, 96h for fish is
considered to be 509 mg/l.
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