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EC number: 201-070-7
CAS number: 77-93-0
Short-term toxicity data
Experimental acute toxicity results of
triethyl citrate are available for aquatic invertebrates (Boettcher and
Wydra, 2010) and aquatic algae (Boettcher and Wydra, 2010). The
short-term toxicity to fish was predicted by means of ECOSAR v1.00
(EPIWIN prediction, by US-EPA), using the SAR for esters.
In a limit 48 -hour immobilisation test
under static conditions, Daphnia magna was used as test organism.
The experiment was conducted according to OECD Guideline 202 and EU
Method C.2. The test concentration was chosen as 100 mg/L, whereby no
immobilisation was recorded after the maximum exposure time. Therefore,
the NOEC(48h) was determined to be equal or greater than 100 mg/L. LOEC
and LC50 values are greater than 100 mg/L.
The freshwater green algae Pseudokirchneriella
subcapitata was used as test organism in a toxicity experiment
according to OECD Guideline 201 and EU Method C.3. A limit test was
conducted with a substance concentration of 100 mg/L. Concerning growth
rate and biomass, the NOEC and LOEC values were determined to be at
least 100 mg/L after an exposure period of 72 h. The NOEC values might
even be higher than this concentration, but concentrations in excess of
nominal 100 mg test item/L or the limit of solubility have not been
tested according to the recommendations of the test guidelines. The EC50
values, concerning both effect bases, were clearly higher than 100 mg/L.
No toxic effects against algae were observed at the limit of water
solubility under these test conditions.
The short-term toxicity to fish was
predicted by ECOSAR v1.00, which resulted in a LC50(96h) of 112.02 mg/L,
concerning SAR for ester. The experimentally determined water solubility
of the substance (58.1 g/L, Villa, 2011) as well as the logPow of 1.17
(Villa, 2011) were used as input.
Long-term toxicity data
No chronic investigations were performed
regarding toxicity towards aquatic biota for triethyl citrate. Taken
into account the available experimental results, the substance can be
considered to be rapidly degraded in the aquatic environment and the
bioaccumulation potential is low. With respect to animal welfare, no
long-term study is intended in accordance with REACH Regulation.
Toxicity to aquatic microorganisms
Since the substance was found to be readily
biodegradable (Feil, 2010), no activated sludge respiration inhibition
test needs to be conducted in accordance with REACH, Annex VIII, Section
9.1.4, Column 2. Furthermore, in the toxicity control of the
biodegradation test conducted according to OECD Guideline 301 F no
inhibition of the activated sludge was observed and the PNEC STP can be
calculated with the help of the applied test concentration (Guidance
from ECHA, Chapter R.10, Part R.10.4.2, 2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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