Registration Dossier
Registration Dossier
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EC number: 202-426-4 | CAS number: 95-51-2
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation: aquatic / sediment
- Type of information:
- other: BUA report
- Adequacy of study:
- other information
- Reliability:
- other: BUA report
- Rationale for reliability incl. deficiencies:
- other: BUA report
Data source
Referenceopen allclose all
- Reference Type:
- other: BUA Report
- Title:
- Unnamed
- Year:
- 1 991
- Reference Type:
- publication
- Title:
- Toxicity, biodegradability, and accumulation of a number of Cl/N-containing compounds for classification and establishing water quality criteria
- Author:
- Canton JH, Slooff W, Kool HJ, Struys J, Pouw TJM, Wegman RCC, Piet GJ
- Year:
- 1 985
- Bibliographic source:
- Regulatory Toxicology and Pharmacology 5, 123-131
- Reference Type:
- publication
- Title:
- The list of the existing chemical substances tested on biodegradability by microorganisms or bioaccumulation in fish body by CITI
- Author:
- MITI (Ministry of International Trade and Industry)
- Year:
- 1 987
- Bibliographic source:
- pages 14 and 21, January 1987
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 982
- Reference Type:
- publication
- Title:
- Waterborne methylene bis(2-chloroaniline) and 2-chloroaniline contamination around Adrian, Michigan
- Author:
- Parris GE, Diachenko GW, Entz RC, Poppiti JA, Lombardo P, Rohrer TK, Hesse JL
- Year:
- 1 980
- Bibliographic source:
- Bull. Environm. Contam. Toxicol. 24, 497-503
Materials and methods
- Principles of method if other than guideline:
- BUA report
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-chloroaniline
- EC Number:
- 202-426-4
- EC Name:
- 2-chloroaniline
- Cas Number:
- 95-51-2
- Molecular formula:
- C6H6ClN
- IUPAC Name:
- 2-chloroaniline
Constituent 1
Results and discussion
- Details on results:
- BUA report
Any other information on results incl. tables
BUA report:
In one publication, the reported log Pow values of o-chloroaniline of 2.0 resulted in a calculated a bioconcentration factor of 20 and thus a weak bioaccumulation potential for free o-chloroaniline was indicated. The calculation was performed according to Ross and Welch (log BCF = 0.76 log Pow - 0.23).
A second publication reports a BCF of 4 from a Pow value of 1.92. This publication does not state to the calculation equation.
The MITI list categorizes o-chloroaniline to be not or weakly bioaccumulative in fish.
There is one indication that o-chloroaniline may be bound covalently to macromolecules in the muscle tissue of carp.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
