Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
other information
Study period:
From February 24, 1993 to February 28, 1993
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Although the study has been conducted according to GLP guidelines, no final report was drafted. Based on the data summary alone it is difficult to establish whether GLP/OECD guidelines have been followed in detail.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1993
Report date:
1993

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
not specified
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
N-[3-(dimethylamino)propyl]acrylamide
EC Number:
223-342-4
EC Name:
N-[3-(dimethylamino)propyl]acrylamide
Cas Number:
3845-76-9
Molecular formula:
C8 H16 N2 O
IUPAC Name:
N‐[3‐(dimethylamino)propyl]prop‐2‐enamide
Details on test material:
In the study report no information is provided about the exact composition of the material tested. However, the DIMAPA test sample was taken at the end of the production process at "Ringleitung P10" which is the same sampling point as used for substance analytical identification.

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
ca. 57 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)

Any other information on results incl. tables

Sublethal observations / clinical signs:
  deaths
 conc. (mg/L)  24h  48h  72h  96h
 0  0  0  0  0
 50  0  0  0  0
 60  0  3  3  1
 70  0  6  3  1
 80  1  7  2  0
 90  1  8  1  0
 100  3  7  0  0

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
Under the test conditions applied the LC50(96h) for D. rerio was established at 57 mg/L.