Registration Dossier
Registration Dossier
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EC number: 223-342-4 | CAS number: 3845-76-9
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 2001
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Although the study has been conducted according to GLP guidelines, no final report was drafted. The data summary lacks detail on: identity/composition of test material, materials and methods which makes it difficult to interpret the available data and to reproduce the study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 001
- Report date:
- 2001
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- N-[3-(dimethylamino)propyl]acrylamide
- EC Number:
- 223-342-4
- EC Name:
- N-[3-(dimethylamino)propyl]acrylamide
- Cas Number:
- 3845-76-9
- Molecular formula:
- C8 H16 N2 O
- IUPAC Name:
- N‐[3‐(dimethylamino)propyl]prop‐2‐enamide
- Details on test material:
- In the study report no information is provided about the exact composition of the material tested. However, the DIMAPA test sample was taken at the end of the production process at "Ringleitung P10" which is the same sampling point as used for substance analytical identification.
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: specially selected polyvalent microorganisms (air-, soil- and water species)
- Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 15.3 mg/L
- Based on:
- other: 10 mgC/L
- Initial conc.:
- 30.6 mg/L
- Based on:
- other: 20 mgC/L
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- Abiotic degradation: ca. 17%
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- it is stated that the test can be considered valid as the criteria for the reference substance have been fulfilled.
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- 28-day biodegradation of DIMAPA after product sample loads of 15.3 and 30.6 mg/l (10 and 20 mg C respectively) was 0%. DIMAPA should therefore, under the test conditions applied, be considered not readily biodegradable.
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