Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: RELIABLE SUMMARY REPORT.
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
review article or handbook
Title:
IUCLID DATASET SUBSTANCE ID:68512-62-9
Author:
EUROPEAN COMMISSION - EUROPEAN CHEMICALS BUREAU
Year:
2000
Bibliographic source:
IUCLID DATASET SUBSTANCE ID:68512-62-9 PG 35

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: DRAIZE TEST
Deviations:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Clarified oils (petroleum), catalytic cracked
EC Number:
265-064-6
EC Name:
Clarified oils (petroleum), catalytic cracked
Cas Number:
64741-62-4
IUPAC Name:
64741-62-4

Test animals

Species:
rabbit
Strain:
New Zealand White

Test system

Type of coverage:
not specified
Preparation of test site:
other: ABRADED AND NOT ABRADED
Vehicle:
not specified
Controls:
not specified
Duration of treatment / exposure:
24h
Observation period:
14 days
Number of animals:
6

Results and discussion

In vivo

Results
Irritation parameter:
primary dermal irritation index (PDII)
Basis:
mean
Time point:
other: 0.2
Max. score:
8
Reversibility:
no data

Any other information on results incl. tables

A mean primary dermal irritation index of 0.2 out of a maximum score of 8.0 indicated that the test substance was minimally irritating.

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: not specified
Conclusions:
minimally irritating