Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013 - 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well performed OECD study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report Date:
2014

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
1.41
Temp.:
23 °C
pH:
> 6.3 - < 6.6
Details on results:
determ. no. stock solution water test substance test substance Log Pow
conc. in n-octanol conc. in water
[ml] [ml] [mg/l] [mg/l]

A1 5 10 656,1 24,7 1,42
A2 5 10 662,6 25,3 1,42
B1 10 10 697,3 26,5 1,42
B2 10 10 676,6 27,2 1,40
C1 20 10 711,0 28,1 1,40
C2 20 10 713,8 29,2 1,39
mean 1,41

Recovery Rate of the test substance: 96 - 99 %

Applicant's summary and conclusion

Conclusions:
The Log Pow of the substance is 1.41 at 23 °C
Executive summary:

The partition coefficient n-octanol / water of the substance was determined according to OECD guideline 107 with the shake flask method.

The Log Pow was found to be 1.41 at 23 °C: