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EC number: 201-906-0 | CAS number: 89-41-8
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2013 - 2014
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: well performed OECD study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- no
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 3-nitro-p-anisic acid
- EC Number:
- 201-906-0
- EC Name:
- 3-nitro-p-anisic acid
- Cas Number:
- 89-41-8
- Molecular formula:
- C8H7NO5
- IUPAC Name:
- 4-methoxy-3-nitrobenzoic acid
Constituent 1
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 1.41
- Temp.:
- 23 °C
- pH:
- > 6.3 - < 6.6
- Details on results:
- determ. no. stock solution water test substance test substance Log Pow
conc. in n-octanol conc. in water
[ml] [ml] [mg/l] [mg/l]
A1 5 10 656,1 24,7 1,42
A2 5 10 662,6 25,3 1,42
B1 10 10 697,3 26,5 1,42
B2 10 10 676,6 27,2 1,40
C1 20 10 711,0 28,1 1,40
C2 20 10 713,8 29,2 1,39
mean 1,41
Recovery Rate of the test substance: 96 - 99 %
Applicant's summary and conclusion
- Conclusions:
- The Log Pow of the substance is 1.41 at 23 °C
- Executive summary:
The partition coefficient n-octanol / water of the substance was determined according to OECD guideline 107 with the shake flask method.
The Log Pow was found to be 1.41 at 23 °C:
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