Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 430-010-4 | CAS number: 12160-44-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The water solubility of the test substance is very low. The test media were analysed for iron content in order to demonstrate equilibration and stability of iron potassium oxide during the tests. Throughout the test no dissolved iron was detected at or above the Iimit of determination of 0.1 mg/L at the single loading rate of 1000 mg/L. No mortality or any other effects were noted in Daphnia magna exposed for 48 hours to a WAF prepared at a loading rate of 1000 mg/L. Therefore, an LC50 value cannot be reliably determined from the test. According to REACH guidance R7a (Appendix 7.8-1) for substances that show no effect at the limit of solubility, and for which all reasonable efforts were made to obtain and maintain the highest possible concentration over the whole test duration, the limit value is to be used for risk assessment. As these criteria were met, the 48-h EC50 for aquatic invertebrates is determined at >1.0 mg/L (limit of solubility).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 mg/L
Additional information
Acute toxicity to aquatic invertebrates was determined in a limit test performed according to the OECD guideline 203 and in compliance with GLP criteria. As the test substance was sparingly soluble in water, a water accommodated fraction was produced using a loading rate of 1000 mg/L. Daphnia magna (10 per concentration) were exposed to the test medium and a control for 48 hours under static conditions. Samples for analysis of the actual concentration were taken at the start of the test and after 48 hours. At the loading rate of 1000 mg/L, analytical concentrations of dissolved iron were below the Iimit of detection (0.1 mg/L) in all. The concentration of suspended iron was appr. 0.4 mg/L at the start and end of the study. No immobilisation of Daphnids or other toxic effects were noted at 24 and 48 hours. Based on these findings the 48-h EC50 is determined at > 1000 mg/L (based on the loading rate).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.