Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-232-9 | CAS number: 64771-71-7 A combination of normal paraffins having carbon numbers predominantly greater than C10 obtained by urea adduction or molecular sieve processes.
Endpoint summary
Administrative data
Description of key information
Acute Toxicity-Oral LD50 > 5000 mg/kg in rats (OECD TG 401)
Acute Toxicity-Dermal LD50 > 2000 mg/kg in rabbits and rats (OECD TG 402)
Acute Toxicity-Inhalation LC50 > 5000 mg/m3 (OECD TG 403)
Key value for chemical safety assessment
Additional information
The acute toxicity of Paraffins (petroleum), normal C>10 has been fully evaluated by a read across from substances from two categories: C9 -C14, aliphatics, < 2% aromatics and C14 -C20, aliphatics, < 2% aromatics. All of the animal studies were performed in a manner similar or equivalent to currently established OECD guidelines. Based on the provided data, Paraffins (petroleum), normal C>10 are expected to have a low order of acute toxicity by the oral, dermal, and inhalation routes of exposure.
Justification for classification or non-classification
Paraffins (petroleum), normal C>10 is a substance minimally toxic via ingestion where the LD50 is >5000 mg/kg, via dermal exposure where the LD50 is >2000mg/kg, and by inhalation where the LC50 > 5000 mg/m3. These findings do not warrant classification of Paraffins (petroleum), normal C>10 under the new Regulation (EC) 1272/2008 on classification, labeling and packaging of substances and mixtures (CLP) and under the Directive 67/548/EEC for dangerous substances and Directive 1999/45/EC for preparations (DSD/DPD). However, C9-C14 aliphatic, < 2% aromatic hydrocarbons (category on which is based the read across for the substance C10 -C17, n-alkanes), and consequently, the substance "Paraffins (petroleum), normal C>10" are classified under EU CLP guidelines as a Category 1 aspiration hazard based on its physical and chemical properties (hydrocarbon fluid, viscosity ≤ 20.5 mm2/s) and as an R65 aspiration hazard under the EU DSD/DPD.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
