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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Acute Toxicity-Oral LD50 > 5000 mg/kg in rats (OECD TG 401)
Acute Toxicity-Dermal LD50 > 2000 mg/kg in rabbits and rats (OECD TG 402)
Acute Toxicity-Inhalation LC50 > 5000 mg/m3 (OECD TG 403)

Key value for chemical safety assessment

Additional information

The acute toxicity of Paraffins (petroleum), normal C>10 has been fully evaluated by a read across from substances from two categories: C9 -C14, aliphatics, < 2% aromatics and C14 -C20, aliphatics, < 2% aromatics.  All of the animal studies were performed in a manner similar or equivalent to currently established OECD guidelines.  Based on the provided data, Paraffins (petroleum), normal C>10 are expected to have a low order of acute toxicity by the oral, dermal, and inhalation routes of exposure.

Justification for classification or non-classification

Paraffins (petroleum), normal C>10 is a substance minimally toxic via ingestion where the LD50 is >5000 mg/kg, via dermal exposure where the LD50 is >2000mg/kg, and by inhalation where the LC50 > 5000 mg/m3.  These findings do not warrant classification of Paraffins (petroleum), normal C>10 under the new Regulation (EC) 1272/2008 on classification, labeling and packaging of substances and mixtures (CLP) and under the Directive 67/548/EEC for dangerous substances and Directive 1999/45/EC for preparations (DSD/DPD). However, C9-C14 aliphatic, < 2% aromatic hydrocarbons (category on which is based the read across for the substance C10 -C17, n-alkanes), and consequently, the substance "Paraffins (petroleum), normal C>10" are classified under EU CLP guidelines as a Category 1 aspiration hazard based on its physical and chemical properties (hydrocarbon fluid, viscosity ≤ 20.5 mm2/s) and as an R65 aspiration hazard under the EU DSD/DPD.