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Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
31 March 2020 to 29 April 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
2016
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Remarks:
Date of Inspection: 10-17 December 2019; Date of Signature on Certificate: 24 February 2020
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
-47.3 °C
Remarks on result:
other: This is the glass transition temperature

Preliminary Test

Starting from 250°C, the weight of the sample decreased significantly. At 282°C, the sample weight had decreased by 25%.

After the experiment, a dark brown molten residue remained in the sample container (original colour: light orange). The change of the colour indicated reaction and/or decomposition of the test item.

 

Main Study

In Experiment 1, during cooling, a glass transition was observed between -40°C and -90°C.

During heating, glass transition was observed between -75°C and -25°C, this is observed as a step in the baseline. The inflection point of the glass transition effect was -47.091°C. 

After the experiment, a dark brown molten residue remained in the sample container (original colour: light orange). The change of the colour indicated reaction and/or decomposition of the test item.

Experiment 2 was performed as a duplicate of Experiment 1.  Similar results as in Experiment 1 were obtained. The inflection point of the glass transition effect was -47.556°C. After the experiment, the residue remained in the sample container was unchanged compared to the original test item appearance.

The glass transition temperature was determined as the mean inflection point of Experiment 1(-47.091°C) and Experiment 2 (-47.556°C).

Conclusions:
No melting point was determined. A glass transition of the test item was observed at -47.3°C.
Executive summary:

Using differential scanning calorimetry in accordance with OECD Guideline 102 (1995) and EC Guideline A1 (2016), no melting point was determined. A glass transition of the test item was observed at -47.3°C.

Description of key information

A glass transition of the test item was observed at -47.3°C; OECD 102; Jovic Madzarevic, Z. (2020)

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-47.3 °C

Additional information

No melting point is observed and instead a glass transition temperature is reported. For the purpose of chemical safety assessment, the glass transition temperature was used as the key value to support exposure assessment.

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