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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
9 May 2018-10 May 2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP study
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Type of method:
capillary method
Key result
Melting / freezing pt.:
181.6 °C
Atm. press.:
1 013.25 hPa
Conclusions:
The melting temperature of 2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol- 5-yl)propanoyl]amino]-2-methyl-propanoic acid Trifluoroacetic acid salt (1:1) CAS n. 1446013-08-6 is 181.6°C at 1013.25 hPa.
Executive summary:

The melting point of 2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol- 5-yl)propanoyl]amino]-2-methyl-propanoic acid Trifluoroacetic acid salt (1:1) CAS n. 1446013-08 -6 was determined by capillary method in compilance with EU Method A.1 (Melting / Freezing Temperature).

The melting temperature of 2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol- 5-yl)propanoyl]amino]-2-methyl-propanoic acid Trifluoroacetic acid salt (1:1) CAS n. 1446013-08-6 is 181.6°C at 1013.25 hPa.

Description of key information

according to Guideline: EU Method A.1 (Melting / Freezing Temperature)

Deviations: no

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
181.6 °C

Additional information