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Diss Factsheets

Administrative data

Endpoint:
density, other
Remarks:
Apparent Specific Gravity
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26/09/2018 - 02/10/2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non-GLP study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report date:
2019

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: ASTM D 5057-10.
GLP compliance:
no
Type of method:
other: Screening of the Apparent Specific Gravity by reading the volume of a quantity of weighed sample placed in a cylinder.
Remarks:
ASTM D5057-10

Test material

Constituent 1
Chemical structure
Reference substance name:
2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-imidazol-5-yl)propanamido]-2-methylpropanoic acid; trifluoroacetic acid
EC Number:
815-122-7
Cas Number:
1446013-08-6
Molecular formula:
C27H27F3N4O7
IUPAC Name:
2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-imidazol-5-yl)propanamido]-2-methylpropanoic acid; trifluoroacetic acid
Test material form:
solid: particulate/powder
Details on test material:
Target Substance Molecular Formula: C27H27F3N4O7
Target Substance Molecular Weight: 576.51 g/mol
Batch Number: 160004
Physical form and colour: Solid, White powder
Storage: Store at 2÷8°C

Results and discussion

Density
Type:
other: Apparent Specific Gravity
Density:
ca. 0.54 other: Kg/dm3
Temp.:
25 °C

Applicant's summary and conclusion

Conclusions:
The Density measurement of test sample gave the following value:
Weight (g): 205.030
Volume (ml): 380
Apparent specific gravity [Kg/dm3]: 0.540 ± 0.017
Executive summary:

A quantity of weighed sample was placed in a cylinder and its volume read. The ratio between the weight in

grams and the volume in ml determines the apparent specific Gravity.

The method used was the ASTM D 5057-10.

The Density measurement of test sample gave the following value:

Weight (g): 205.030

Volume (ml): 380

Apparent specific gravity [Kg/dm3]: 0.540 ± 0.017