Registration Dossier

Administrative data

Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
other: SIDS
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
SIDS for L-Glutamic acid
Author:
OECD
Year:
2013
Report Date:
2013
Reference Type:
other: QSAR-tool
Title:
Estimations Programs Interface (EPI) Suite™ for Microsoft Windows®, v4.10
Author:
US EPA (U.S. Environmental Protection Agency)
Year:
2011

Materials and methods

Test material

Specific details on test material used for the study:
Test material equivalent to submission substance identity:
yes

Test conditions

Details on test conditions:
Details on estimation of bioconcentration
[BASIS FOR CALCULATION OF BCF]
- Estimation software: BCFBAF ver.3.01
- Summary Results:
Log BCF (regression-based estimate): 0.50 (BCF=3.16 L/kg wet-wt)
Biotransformation Half-Life (days): 0.00946 (normalized to 10 g fish)
Log BAF (Arnot-Gobas upper trophic): -0.05 (BAF=0.893 L/kg wet-wt)
Log Kow (experimental): -3.69
Log Kow used by BCF estimates: -3.69
Equation Used to Make BCF estimate: Log BCF = 0.50 (Ionic; Log Kow dependent)
Estimated Log BCF = 0.500 (BCF = 3.162 L/kg wet-wt)

Results and discussion

Bioaccumulation factor
Key result
Type:
BCF
Value:
3.162 dimensionless

Applicant's summary and conclusion

Conclusions:
Using log Kow of -3.69, a BCF of 3.162 was calculated with BCFBAF, version 3.01. This chemical is not expected to bioaccumulate.