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EC number: 200-293-7 | CAS number: 56-86-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- other: SIDS
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- SIDS for L-Glutamic acid
- Author:
- OECD
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): L-Glutamic acid
- Physical state: White powder
- Storage condition of test material: 7 degrees C, protected form moisture and light
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 50 mg/L
- Based on:
- formulation
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- [TEST CONDITIONS]
- Composition of medium: Mineral nutrient solution according to OECD 301 E
- Additional substrate: no
- Test temperature: 22 +/- 2 degrees C
- pH: 7.4 +/- 0.1
- pH adjusted: yes, at test begin if necessary
- Continuous darkness: yes
[TEST SYSTEM]
- Culturing apparatus: the vessels were stirred continuously with magnetic bars
- Number of culture flasks/concentration: two incubation vessels for the test substance concentration and for the inoculum control, one incubation vessel for the reference substance and for the toxicity control
- Method used to create aerobic conditions: by aeration
- Measuring equipment: pH-meter (Corning Ph240), DOC-Analysator (Multi N/C 3000, Analytik Jena), Thermohygrograph (Lufft)
- Test performed in closed vessels due to significant volatility of test substance: no
- Test performed in open system: yes
[SAMPLING]
- Sampling frequency: samples were taken on day 0, 1, 4, 7, 14, 21 and 28
- Sampling method: no data- Sterility check if applicable: no- Sample storage before analysis: no data
[CONTROL AND BLANK SYSTEM]
- Inoculum blank: nutrient solution and inoculums
- Abiotic sterile control: no data
- Toxicity control: test and reference item in test concentration and inoculum
Reference substance
- Reference substance:
- other: Sodium acetate, puriss.
Results and discussion
- Test performance:
- [CARBON CONTENT OF THE TEST SUBSTANCE]
The test substance was added at a test concentration of 50 mg/L corresponding to a carbon content of 20.4 mg C/L in the test vessels.
[COURSE OF THE BIODEGRADATION]
The total amount of DOC was analysed in seven measurements over a period of 28 days.
In the toxicity control containing both test and reference substance, the biodegradation came to 93% after 14 days. The biodegradation of the reference substance was not inhibited by the test substance.The test substance in the test concentration of 50 mg/L reached the level of 10% (begin of the biodegradation) after 1 day. In the 10-d-window a biodegradation rate > 70% was reached. After 28 days the biodegradation came to a maximum of 97%.The validity criteria of the test are fulfilled according to the guideline.
% Degradationopen allclose all
- Parameter:
- % degradation (DOC removal)
- Value:
- 0
- Sampling time:
- 1 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 90
- Sampling time:
- 4 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 92
- Sampling time:
- 7 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 95
- Sampling time:
- 14 d
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 97
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- In order to check the activity of the test system sodium acetate in a concentration of 130 mg/L was used as functional control. The adaptation phase changed after 1 day into the degradation phase (degradation >= 10%). The course of the degradation phase was rapid and reached a degradation rate of 96% already on day 14. The quality criterion degradation >= 70% after 14 days was fulfilled.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The biodegradation of L-glutamic acid measured by DOC removal was 97% after 28 days. L-glutamic acid is considered to be readily biodegradable.
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