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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
13 Aug 2018 - 16 Oct 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Cross-reference
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
Version / remarks:
1998
Deviations:
no
GLP compliance:
yes
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
Sebacohydrazide
EC Number:
213-126-8
EC Name:
Sebacohydrazide
Cas Number:
925-83-7
Molecular formula:
C10H22N4O2
IUPAC Name:
sebacohydrazide
Test material form:
solid: particulate/powder
Details on test material:
Test item name (as stated in report): SDH
Test item storage: at room temperature protected from light

Results and discussion

Water solubility
Key result
Water solubility:
0.208 g/L
Conc. based on:
test mat. (dissolved fraction)
Loading of aqueous phase:
0.975 g/L
Incubation duration:
>= 24 - <= 72 h
Temp.:
20 °C
pH:
>= 8.4 - <= 8.5
Details on results:
- Concentration analysed after 24, 48 and 72 hours of stirring: 0.210 g/L, 0.208 g/L and 0.206 g/L, resp.
- Maximum difference meets the criterion of ≤ 15% (i.e. 1.7%)
- The mean of the three concentrations was reported as the water solubility of the substance.

Any other information on results incl. tables

A small response at the retention time of the test item was detected in the chromatogram of the pretreated sample from the blank water mixture.  The response was lower than the intercept of the calibration curve and no concentration could be calculated. As the response was so low, it was considered to have no impact on the study results.

Applicant's summary and conclusion

Conclusions:
The water solubility of the substance at 20°C was determined to be 0.208 g/L (flask method).