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Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
06 August 2018 - 19 October 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Cross-reference
Reason / purpose for cross-reference:
reference to same study
Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
06 August 2018 - 19 October 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to same study
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling Point)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Version / remarks:
1996
Deviations:
no
GLP compliance:
yes
Type of method:
differential scanning calorimetry
Key result
Decomposition:
yes
Decomp. temp.:
>= 225 °C

Two experiments were performed to investigate the melting and boiling behaviour of the substance.

 

DSC EXPERIMENT 1

An endothermic effect was observed between 150°C and 225°C followed by an exothermic effect starting at 225°C. The first effect was ascribed to melting of the test item (see endpoint 4.2). The exothermic effect was probably caused by reaction and/or decomposition of the test item. After the experiment, a dark brown molten residue remained in the sample container (original colour: white). The change of the colour indicated reaction and/or decomposition of the test item. Based on this visual observation, it was concluded that the test item had molten and that the change of the colour demonstrated reaction and/or decomposition of the test item.

 

DSC EXPERIMENT 2

Performed in order to investigate the endothermic effect, see endpoint 4.2.

 

DATA HANDLING

Reaction and/or decomposition of the test item was observed in the DSC experiment at temperatures of > 225°C (> 498K) and confirmed by change of colour (after the experiment). Therefore the test item has no boiling temperature. 

Conclusions:
Boiling of the substance was not observed below the temperature at which reaction and/or decomposition started (i.e. at approx. 225°C).

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Version / remarks:
1998
Deviations:
no
GLP compliance:
yes
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
Sebacohydrazide
EC Number:
213-126-8
EC Name:
Sebacohydrazide
Cas Number:
925-83-7
Molecular formula:
C10H22N4O2
IUPAC Name:
sebacohydrazide
Test material form:
solid: particulate/powder
Details on test material:
Test item name (as stated in report): SDH
Test item storage: at room temperature protected from light

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
190.8 °C

Any other information on results incl. tables

Two experiments were performed to investigate the melting and boiling behaviour of the substance.

 

DSC EXPERIMENT 1

An endothermic effect was observed between 150°C and 225°C followed by an exothermic effect starting at 225°C. The extrapolated onset temperature of the first effect was 190.887°C. The endothermic effect was most likely caused by melting of the test item. The exothermic effect was probably caused by reaction and/or decomposition of the test item (see endpoint 4.3).

 

DSC EXPERIMENT 2

In order to investigate the endothermic effect, in Experiment 2 heating was stopped directly after the melting effect. The extrapolated onset temperature was 190.681°C. After the experiment, a white molten residue remained in the sample container (original colour: white). It demonstrated that melting was the reason for the endothermic effect.

 

DATA HANDLING

The melting temperature was determined as the mean melting temperature of Experiment 1 (190.887°C) and Experiment 2 (190.681°C).

Applicant's summary and conclusion

Conclusions:
The melting temperature of the substance was determined to be 190.8°C.