Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-04-12
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Determination of the melting point by the thermoanalytical technique DSC
GLP compliance:
no
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Test material form:
solid: particulate/powder

Results and discussion

Melting / freezing pointopen allclose all
Key result
Melting / freezing pt.:
>= 39.63 - <= 222.28 °C
Remarks on result:
other:
Remarks:
peak at 139.57°C
Key result
Melting / freezing pt.:
>= 260.53 - <= 289.36 °C
Remarks on result:
other:
Remarks:
peak at 260.53°C

Applicant's summary and conclusion

Conclusions:
The DSC shows an endothermic peak which covers a wide range between 39°C and 222°C, with a peak at 139°C.
Executive summary:

A determination of the thermal stability of the test item by DSC (Differential Scanning Calorimetry) was performed with a DSC Mettler TOLEDO DSC 1, using a perforated crucible.

The DSC shows an endothermic peak which covers a wide range between 39°C and 222°C, with a peak at 139°C. This endothermic peak is considerably broad, over 180°C. It does not seems to be melting point. It might be a relaxation phenomena due to the evaporation of water.