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Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
other: Procedure designed to be compatible with that given in European Commission Guidance Document EUR 20268 ‘Determination of Particle Size Distribution, Fibre Length and Diameter Distribution of Chemical Substances’ (2002).
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
cascade impaction
Type of particle tested:
primary particle
Mass median aerodynamic diameter:
other:
Remarks on result:
other: Too few particles were of a size less than 10.0 μm to allow accurate assessment of the mass median aerodynamic diameter.
Key result
Remarks on result:
not determinable
No.:
#1
Size:
< 100 µm
Distribution:
84.7 %
No.:
#2
Size:
< 10 µm
Distribution:
2.07 %
No.:
#3
Size:
< 5.5 µm
Distribution:
< 1.34 %
Conclusions:
Particle size data acquired for the test item is as follows:
Percentage of test item with an inhalable particle size <100 μm - 84.7%
Percentage of test item with a thoracic particle size <10.0 μm - 2.07%
Percentage of test item with a respirable particle size <5.5 μm - 1.34%

Description of key information

Particle size data acquired for the test item is as follows:

Percentage of test item with an inhalable particle size <100 μm - 84.7%

Percentage of test item with a thoracic particle size <10.0 μm - 2.07%

Percentage of test item with a respirable particle size <5.5 μm - 1.34%

Additional information