Registration Dossier

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data are being assessed for the use in a category approach. Available information are being judged as reliable with restrictions since it was conducted by a modeled and measured data.
Remarks:
Data are being assessed for the use in a category approach. Available information are being judged as reliable with restrictions since it was conducted by a modeled and measured data.
Justification for type of information:
Important considerations for the read-across were:

Sodium Olivoyl Glutamate (the target chemical) has similar physico-chemical properties as the others members:
- "Aliphatic acid category" (the source chemicals);
- "Amino acid alkyl amides category" (the source chemicals);
- Sodium oleoyl glutamate (the source chemicals);

Key points are that the members share:
- the same structural features
- similar metabolic pathways
- common levels and mode of human health related effects
- function.
Qualifier:
no guideline available
Principles of method if other than guideline:
not specified
GLP compliance:
not specified
Specific details on test material used for the study:
not specified
Oxygen conditions:
not specified
Inoculum or test system:
not specified
Details on inoculum:
not specified
Details on study design:
not specified
Preliminary study:
not specified
Test performance:
not specified
Key result
Parameter:
other: See Conclusion
Remarks:
See Conclusion
Remarks on result:
other: See Conclusion
Remarks:
See Conclusion
Details on results:
See Conclusion
Key result
Remarks on result:
other: See Conclusion
Remarks:
See Conclusion
Validity criteria fulfilled:
yes
Interpretation of results:
readily biodegradable
Conclusions:
Biodegradation studies or model estimations for single and multi-component aliphatic acids generally confirm that the extent of biodegradation observed in 28 days meets the ready biodegradability criterion (>60%). In some cases, insufficient sampling points were included in the tests to determine whether or not the 10-day window was met and thus are insufficient to demonstrate ready biodegradability. When the 10-day window was not met or less than 60% biodegradation was observed in 28 days, it is likely that the aliphatic acids tested were not fully in solution.
Executive summary:

Aliphatic Acids category members are readily biodegradable and are not expected to bioaccumulate.

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Justification for type of information:
Important considerations for the read-across were:

Sodium Olivoyl Glutamate (the target chemical) has similar physico-chemical properties as the others members:
- "Aliphatic acid category" (the source chemicals);
- "Amino acid alkyl amides category" (the source chemicals);
- Sodium oleoyl glutamate (the source chemicals);

Key points are that the members share:
- the same structural features
- similar metabolic pathways
- common levels and mode of human health related effects
- function.
Key result
Remarks on result:
not measured/tested
Key result
Remarks on result:
not measured/tested
Conclusions:
Overall, considering available data on the category members, the substance deemed to be readily biodegradable in water.
Executive summary:

The substance deemed to be readily biodegradable in water.

Description of key information

Several studies are available in the scientific literature which investigated the biodegradation.

Almost all results support the ready biodegradation of these substances.

Overall, the substance deemed to be readily biodegradable in water.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

Overall, considering available data on the category members, the substance deemed to be readily biodegradable in water.